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Nanoneedle Skin Patch to Inject Drugs Into Cells

Nanoneedle Skin Patch to Inject Drugs Into Cells


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nanoneedle skin patch to inject drugs into cells - Nanoneedle Skin Patch to Inject Drugs Into Cells

Delivering medicine at once into pores and skin cells the usage of microscopic nanoneedles might permit for extremely efficient remedy of pores and skin stipulations with out injuring the cells which can be handled. Silicon nanoneedles were advanced previously that may do one of these trick, however they’re stiff and may also be painful, as well as to briefly shedding their effectiveness. This is for the reason that nanoneedle arrays are generally put on inflexible silicon wafers.

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“To tackle this problem, we developed a method that enables physical transfer of vertically ordered silicon nanoneedles from their original silicon wafer to a bio-patch,” mentioned Chi Hwan Lee, assistant professor at Purdue University. “This nanoneedle patch is not only flexible but also transparent, and therefore can also allow simultaneous real-time observation of the interaction between cells and nanoneedles.”

Scientists at Purdue University and South Korea’s Hanyang University have now advanced versatile and translucent platform for silicon nanoneedle patches, making an allowance for correct and minimally invasive drug supply immediately into dwelling cells.

The nanopatches cannot most effective be positioned at the pores and skin, however between muscular tissues and inside tissues for long run implantation. For on-skin packages, the patches stay translucent and so the tissue beneath may also be monitored quite neatly whilst it’s therapeutic.

“This means that eight or nine silicon nanoneedles can be injected into a single cell without significantly damaging a cell. So we can use these nanoneedles to deliver biomolecules into cells or even tissues with minimal invasiveness,” mentioned Chi Hwan Lee.

 

Study in Science Advances: Flexible elastomer patch with vertical silicon nanoneedles for intracellular and intratissue nanoinjection of biomolecules…

Via: Purdue University…




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